Respiratory Syncytial Virus

  • single-stranded RNA virus
  • Spread through:
    • airborne droplets
    • direct contact with respiratory secretions
  • RSV replicates in the nasopharynx - causing coryzal symptoms
  • LRTI can begins 2-3 days later, where the virus spreads to the bronchioles

The virus causes inflammatory response:

  • immune cells infiltrate the bronchiolar epithelium which lined the small airways
  • increased mucous production of goblet cells lead to edema → eventually necrosis → regeneration of epithelial cells
  • this leads to small airway obstruction, air trapping, and increase airway resistance
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Table Of Contents
Respiratory Syncytial Virus
The virus causes inflammatory response: