Dyslipidemia

Definition

  • Total cholesterol (TC) > 5.2 mmol/l
  • HDL-C < 1.0 mmol/l (males) < 1.2 mmol/l (females)
  • TG > 1.7 mmol/l
  • LDL-C levels - will depend on the patient’s CV risk (based on table below)
    dyslipidemia-ldl-level.jpeg

Risk Factors

Pathophysiology

Classification

History Taking

Physical Examination

Investigations

Management

Non-pharmacological

1. Therapeutic lifestyle changes

  1. Adhering to healthy dietary patterns
  2. Regular exercise - β‰₯ 150 minutes of moderate intensity exercise per week or 75 minutes a week of vigorous-intensity exercise or an equivalent combination
  3. Avoidance of tobacco smoking
  4. Alcohol restriction
  5. Maintenance of an ideal weight - BMI 20 - 23.5 kg/m2 and waist circumference < 90 cm (men), < 80 cm (women).

2. Medical nutrition therapy (MNT)

  1. Heart-healthy dietary patterns
  2. Plant-based diet
  3. Quarter-Quarter-Half diet

Pharmacological

1. Statins

dyslipidemia-statin.jpeg

2. Lipid Modifying Drugs

dyslipidemia-lipid-modifying-drug.jpeg

Complications

Reference